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butabarbital will reduce the extent or effect of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. The efficacy of hormonal contraceptives may be reduced.butabarbital will minimize the level or effect of glecaprevir/pibrentasvir by influencing